Atlanta's Reynaldo Lopez and his 1.34 ERA take the bump against the Padres with a projected betting line of Atlanta -175.

Jared Jones lost to Chicago in his last outing and now faces them at Wrigley Field. What's the best way to bet this game?

Atlanta is a sizeable favorite in what should be a pitcher's duel. Charlie Morton takes the bump for Atlanta, while the Cubs counter with Javier Assad and his 1.70 ERA.

The Phillies have won all eight starts by Ranger Suarez. He has a 1.50 ERA and 0.72 WHIP. Philly is a -180 home favorite over the Mets.

The Astros are -180 favorites, despite having Spencer Arrighetti and his 8.14 ERA on the mound. However, Oakland is countering with Ross Stripling.

The Pirates' Paul Skedes, last year's top overall draft pick, will make his much-anticipated debut on Saturday against the Cubs at home. The 6-foot-6 starting pitcher has struck out 45 batters…

Our resident underdog player looks to start a new streak by backing a pitcher with the American League's lowest ERA. Logan Gilbert at Seattle visit Minnesota as short 'dogs.

The Cardinals host the Mets as -165 favorites with Sonny Gray on the mound. However, given St. Louis' offensive struggles, there are various ways to back Gray.

Philly has won the First 5 innings moneyline in 20 of its last 21 games. The Phillies host the Blue Jays on Wednesday as -150 favorites behind Aaron Nola.

Cubs rookie pitcher Shota Imanaga and his 0.78 ERA will face San Diego at Wrigley Field. Chicago (-135) has won all six of his starts.